Research Summary:
Dr. James W. Griffith is a clinical psychologist with a strong background in research, statistics, patient-reported outcomes, and behavioral interventions. At the University of Chicago, he is embedded in both the Department of Psychiatry and Behavioral Neuroscience, as well as the Department of Obstetrics and Gynecology, Division of Urogynecology and Reconstructive Pelvic Surgery. This dual appointment allows his lab to focus on the intersection of mental health with a broad range of medical concerns. In addition to his research experience, Dr. Griffith is a licensed clinical psychologist who treats patients with severe depression and anxiety using evidence-based approaches such as cognitive behavior therapy (CBT). The Griffith Lab leverages expertise in clinical assessment, research methodology, and psychometrics to develop clinical measurement tools and behavioral interventions with an emphasis on patient-reported outcomes.
Dr. Francesca Farina is a Research Assistant Professor in the Griffith Lab. A trained neuroscientist, Dr. Farina leads a dedicated line of research on women’s brain health with a particular focus on modifiable factors that influence risk for Alzheimer’s disease and related dementias. Her work emphasizes the importance of early detection, with a goal of identifying both risk and resilience factors that emerge during key life transitions, such as menopause.
Dr. Farina co-leads the PERI-MIND intervention study, designed for perimenopausal and early postmenopausal individuals who may be at increased risk for cognitive decline. Through collaborations with multidisciplinary teams, Dr. Farina aims to close the gap in dementia research that has historically overlooked sex-specific mechanisms.
Beyond the lab, Dr. Farina works actively with patient advocacy groups and community-based organizations to promote brain health literacy and reduce stigma surrounding cognitive decline and neurodegenerative diseases. She is committed to advancing equitable, informed, and proactive approaches to brain health for all.

James William Griffith, PhD
Professor of Obstetrics and Gynecology
Professor of Psychiatry and Behavioral Neuroscience

Francesca Farina, PhD
Research Assistant Professor, Griffith Lab